首页 >> 中医拔罐

看脸识病:出现这些征象,离冠心病不太可能就不远了!

发布时间:2025年11月22日 12:17

糖尿病、糖尿病或者即已样结核病位与的为数众多体来说,脸上则会变黑与冠状颈动脉较宽的导致总体有关[22]。一项划入了500多名组织者的深入研究高亮,脸上则会变黑是冠状颈动脉CTA钙化积分缩减的独立生命危险考量[23]。 脸上变黑为什么与结核病的暴样效用有关?以外指出,脸上变黑和颈动脉粥样变硬的暴样共存类似的生理机制,即DNA修复受损、氧化应激、激素、凝性疟疾等[24-26]。

4

乳突头

乳突头是在乳突周缘成型号的非常丰富磷脂的沉积物质,是一片深蓝色或灰色的透明第一区,与组织受压无关,与磷脂沉积有关[27]。1852年,鼓舞人心的生理学家Virchow就首次提出批评乳突头也许是肺结核的一个生命危险考量[28]。乳突头老年病患者多见,深入研究见到其与高碳水化合物不足症、饮酒、深蓝色素疣、糖尿病、吸烟、糖尿病、结核病等以外系统性[29-31]。 平面图2 乳突头 既往多项深入研究见到,乳突头与结核病彼此间共存系统性性。1974年《新英格兰Medicine》的一篇社论通过对3152名异性恋经过8.5年的随访,结果见到年长病患者再次出现乳突头是将来肺癌结核病的独立生命危险考量[32]。Fernandez AB等划入了23376名组织者,经过8年的随访,结果见到乳突头与结核病的暴样突出系统性[33]。一项划入了10885名组织者的前瞻性队列深入研究经过35年的随访见到,乳突头与将来暴样结核肺结核的效用系统性,并且这种系统性性是独立于年岁和其他结核生命危险考量之外的[34]。 乳突头与结核病系统性的机制以外推测指出与抗氧化剂有关,尤其是与低密度脂蛋白碳水化合物(LDL-C)准确度有关[35,36]。

5

深蓝色疣

深蓝色疣是一种由于非常丰富磷脂的细胞内沉积造成了的皮肤发生变化,其可以再次出现在全身多处,如果再次出现在乳突称为乳突深蓝色疣[37]。 平面图3 乳突附多达的深蓝色疣 一项划入了12745名新社第一区居民随访22年的前瞻性深入研究见到,深蓝色素疣突出缩减了都可为数众多体肺癌结核病、心力衰竭、导致颈动脉粥样变硬疟疾和死亡的效用,并且这种效用的缩减是独立于传统结核病生命危险考量以外的[38]。一项划入了394名给与冠状颈动脉断层扫描定期检查的结核病病患者深入研究见到,关节深蓝色疣与结核病的导致总体系统性[39]。 深蓝色疣缩减结核病暴样率也许与这些病患者体内内皮处理磷脂的能力下降进而造成了抗氧化剂进入肺部内中所膜准确度缩减有关[40]。

6

总结

本文简单地和大家分门别类了一下常见的也许得出论据结核病暴样效用的相貌特南征。严格来说,中所国医学科学院阜外公立医院和清华深入研究团队仍然引导计算机科学的方法就“相貌”在结核病得出论据多方面透过了很有意涵的深入研究[41],这些特南征几乎与抗氧化剂代谢异常、年岁缩减有关,对于临床上结核病病患者的治疗得出论据也许不具备一定的高亮意涵。

平面图4 线性指出也许与结核病共存较突出相似之处的头头部特南征包括:额秃(样际线移至)、肩膀秃、耳垂折痕、耳前折痕、眼袋深、鱼尾纹深、额头水泡深、下颚附多达有水泡、鼻沟、鼻唇沟(法令纹)深、老年斑、口唇驼背等

参考文献:

[1] Frank ST. Aural sign of coronary-artery disease. NEngl J Med. 1973 Aug 9; 289(6): 327-8.[2] Lichstein E, Chadda KD, Naik D, Gupta PK. Diagonalear-lobe crease: prevalence and implications as a coronary risk factor. N EnglJ Med. 1974 Mar 14; 290(11): 615-6.[3] Wang Y, Mao LH, Jia EZ, et al. Relationshipbetween diagonal earlobe creases and coronary artery disease as determined viaangiography. BMJ Open. 2016 Feb 11; 6(2): e008558.[4] Iorgoveanu C, Zaghloul A, Desai A, et al.Bilateral Earlobe Crease as a Marker of Premature Coronary Artery Disease.Cureus. 2018 May 13; 10(5): e2616.[5] Edston E. The earlobe crease, coronary arterydisease, and sudden cardiac death: an autopsy study of 520 individuals. Am JForensic Med Pathol. 2006 Jun; 27(2): 129-33.[6] Christoffersen M, Tybjærg-Hansen A. Visible agingsigns as risk markers for ischemic heart disease: Epidemiology, pathogenesisand clinical implications. Ageing Res Rev. 2016 Jan; 25: 24-41.[7] Agouridis AP, Elisaf MS, Nair DR, Mikhailidis DP.Ear lobe crease: a marker of coronary artery disease? Arch Med Sci. 2015 Dec10; 11(6): 1145-55.[8] Pacei F, Bersano A, Brigo F, et al. Diagonalearlobe crease (Frank's sign) and increased risk of cerebrovascular diseases:review of the literature and implications for clinical practice. Neurol Sci.2020 Feb; 41(2): 257-262.[9] Stoyanov GS, Dzhenkov D, Petkova L, et al. TheHistological Basis of Frank's Sign. Head Neck Pathol. 2021 Jun; 15(2): 402-407.[10] Del Brutto OH, Mera RM, Costa AF, et al. TheAssociation between Earlobe Crease (Frank's Sign) and Abnormal Ankle-BrachialIndex Determination Is Related to Age: A Population-Based Study. Int J VascMed. 2018 Sep 2; 2018: 4735731.[11] Marks DH, Penzi LR, Ibler E, et al. The Medicaland Psychosocial Associations of Alopecia: Recognizing Hair Loss as More Than aCosmetic Concern. Am J Clin Dermatol. 2019 Apr; 20(2): 195-200.[12] Patil VB, Lunge SB. A Study of Correlation ofAngiographic Evaluation of Coronary Artery Disease with AndrogeneticAlopecia-TricoHeart Study. Int J Trichology. 2019 Nov-Dec; 11(6): 227-231.[13] Triantafyllidi H, Grafakos A, Ikonomidis I, et al.Severity of Alopecia Predicts Coronary Changes and Arterial Stiffness inUntreated Hypertensive Men. J Clin Hypertens (Greenwich). 2017 Jan; 19(1):51-57.[14] Kim MW, Shin IS, Yoon HS, et al. Lipid profile inpatients with androgenetic alopecia: a meta-analysis. J Eur Acad DermatolVenereol. 2017 Jun; 31(6): 942-951.[15] Herrera CR, D'Agostino RB, Gerstman BB, et al.Baldness and coronary heart disease rates in men from the Framingham Study. AmJ Epidemiol. 1995 Oct 15; 142(8): 828-33.[16] Matilainen VA, Mäkinen PK, Keinänen-KiukaanniemiSM. Early onset of androgenetic alopecia associated with early severe coronaryheart disease: a population-based, case-control study. J Cardiovasc Risk. 2001Jun; 8(3): 147-51.[17] Shin JW, Kang T, Lee JS, et al. Time-DependentRisk of Acute Myocardial Infarction in Patients With Alopecia Areata in Korea.JAMA Dermatol. 2020 Jul 1; 156(7): 763-771.[18] Sharma KH, Jindal A. Association betweenandrogenetic alopecia and coronary artery disease in young male patients. Int JTrichology. 2014 Jan; 6(1): 5-7.[19] Sharma K, Humane D, Shah K, et al. Androgenicalopecia, premature graying, and hair thinning as independent predictors ofcoronary artery disease in young Asian males. Cardiovasc Endocrinol. 2017 Nov 15;6(4): 152-158.[20] Kumar AB, Shamim H, Nagaraju U. Premature Grayingof Hair: Review with Updates. Int J Trichology. 2018 Sep-Oct; 10(5): 198-203.[21] Mirić D, Fabijanić D, Giunio L, et al.Dermatological indicators of coronary risk: a case-control study. Int JCardiol. 1998 Dec 31; 67(3): 251-5.[22] Kocaman SA, Çetin M, Durakoğlugil ME, et al. Thedegree of premature hair graying as an independent risk marker for coronaryartery disease: a predictor of biological age rather than chronological age.Anadolu Kardiyol Derg. 2012 Sep; 12(6): 457-63.[23] ElFaramawy AAA, Hanna IS, Darweesh RM, et al. Thedegree of hair graying as an independent risk marker for coronary arterydisease, a CT coronary angiography study. Egypt Heart J. 2018 Mar; 70(1): 15-19.[24] Thompson KG, Marchitto MC, Ly BCK, Chien AL.Evaluation of Physiological, Psychological, and Lifestyle Factors Associatedwith Premature Hair Graying. Int J Trichology. 2019 Jul-Aug; 11(4): 153-158.[25] Shin H, Ryu HH, Yoon J, et al. Association ofpremature hair graying with family history, smoking, and obesity: across-sectional study. J Am Acad Dermatol. 2015 Feb; 72(2): 321-7.[26] McDonough PH, Schwartz RA. Premature hairgraying. Cutis. 2012 Apr; 89(4): 161-5.[27] Hanterdsith B. An Evaluation of the Arcus CorneaeFor Age Estimation. Acad Forensic Pathol. 2019 Sep; 9(3-4): 155-162.[28] Brett T, Arnold-Reed D. Familialhypercholesterolaemia: A guide for general practice. Aust J Gen Pract. 2019Sep; 48(9): 650-652.[29] Altschmiedová T, Vaclová M, Vráblík M. Diagnosisof Familial Hypercholesterolaemia on First Sight? The Role of theOphthalmologist in Identifying Patients with Familial Hypercholesterolaemia.Cesk Slov Oftalmol. 2019 Winter; 74(4): 127-131.[30] Masoumpour MB, Jafari P. Is Corneal ArcusIndependently Associated With Incident Cardiovascular Disease in Asians? Am JOphthalmol. 2018 Apr; 188: 184-185.[31] Wu R, Wang JJ, Tai ES, Wong TY. Cardiovascularrisk factors, inflammation, and corneal arcus: the singapore malay eye study.Am J Ophthalmol. 2010 Oct; 150(4): 581-587.e1.[32] Rosenman RH, Brand RJ, Sholtz RI, Jenkins CD.Relation of corneal arcus to cardiovascular risk factors and the incidence ofcoronary disease. N Engl J Med. 1974 Dec 19; 291(25): 1322-4.[33] Fernandez AB, Keyes MJ, Pencina M, et al.Relation of corneal arcus to cardiovascular disease (from the Framingham HeartStudy data set). Am J Cardiol. 2009 Jan 1; 103(1): 64-6.[34] Schou AL, Mølbak ML, Schnor P, et al. Alcoholconsumption, smoking and development of visible age-related signs: aprospective cohort study. J Epidemiol Community Health. 2017 Dec; 71(12): 1177-1184.[35] Ang SM, Williams BK, Shields CL. Rings on theeyes, matters of the heart. Indian J Ophthalmol. 2018 Apr; 66(4): 494.[36] Ford TJ, Rocchiccioli P. A keen eye for risk.BMJ. 2018 Feb 1; 360: j5884.[37] Knebel B, Müller-Wieland D, Kotzka J.Lipodystrophies-Disorders of the Fatty Tissue. Int J Mol Sci. 2020 Nov 20; 21(22):8778.[38] Christoffersen M, Frikke-Schmidt R, Schnohr P, etal. Xanthelasmata, arcus corneae, and ischaemic vascular disease and death ingeneral population: prospective cohort study. BMJ. 2011 Sep 15; 343: d5497.[39] Kitahara H, Nakayama T, Fujimoto Y, Kobayashi Y.Association between Achilles tendon xanthoma and severity of coronary arterydisease in patients undergoing percutaneous coronary intervention. J Cardiol.2020 Jun; 75(6): 654-658.[40] Laftah Z, Al-Niaimi F. Xanthelasma: An Update onTreatment Modalities. J Cutan Aesthet Surg. 2018 Jan-Mar; 11(1): 1-6.[41] Lin S, Li Z, Fu B, et al. Feasibility of usingdeep learning to detect coronary artery disease based on facial photo. EurHeart J. 2020 Dec 7; 41(46): 4400-4411.。

抗感染药
感冒咳嗽有黄痰怎么办
儿童感冒咳嗽可以喝急支糖浆吗
感冒咳嗽怎么缓解
抑郁症

上一篇: 羽生结弦:今天被冰山讨厌了 要日行十善才行

下一篇: 大年三十,他们的年夜饭来自麦当劳、海底捞

友情链接